Blender 2.80, e6eb7b9ccee1
Linux, Xorg-server 1.20.3

I use xorg with mouse acceleration disabled, and with the TransformationMatrix option to change the cursor's speed. This configuration works great with programs, including Blender 2.79b, but in 2.80 the cursor "jumps" towards the bottom right corner after I resize, move, etc.. Turns out it was the fault of the TransformationMatrix option.

To reproduce:
Create a file, /etc/X11/xorg.conf.d/50-mouse-speed.conf, with the contents:

Section "InputClass"
	Identifier "My Mouse"
	MatchIsPointer "yes"
	Option "TransformationMatrix" "3 0 0 0 3 0 0 0 1"
EndSection

Restart xorg
Open blender 2.80, and resize the cube, move it, rotate it etc.
You will see it "jumping"
With

Option "TransformationMatrix" "0.5 0 0 0 0.5 0 0 0 1"

it will jump towards top left.
With

Option "TransformationMatrix" "1 0 0 0 1 0 0 0 1"

(the default values) it works normal.